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G theoretically suitable for repeated booster shots. Furthermore, recent innovations inG theoretically suitable for repeated booster shots. Furthermore, recent innovations in plasmid host strain and vector engineering increased plasmid manufacturing quality and yield, transgene expression levels, transfection efficiency, for a safer and more effective gene platform [10,11] compared to first
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Tend to be more difficult and expensive to store and toTend to be more difficult and expensive to store and to distribute, since viability must be maintained, often requiring formulation approaches [7] for stabilization . On the other hand, killed/inactivated vaccines have a number of disadvantages. The major challenge is that since cells are never infected with the live microbe, these vacci
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Up as compared with the corresponding values of the control. Data presented in tables 3 show that the rats exposed to the two types of vapours encountered a significant decrease in the norepinephrine, dopamine and serotonin contents of the hippocampus as compared with the control group. On other hand, no significant changes were found in norepinephrine and serotonin between the leaded or the unlea
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Ns [102, 106]. In contrast, IDPs are charged proteins, thus they can control their interfacial absorption onto solid surfaces [106]. Experiments, in silico, suggest that intrinsically disordered peptides absorbed to a surface with a complementary pattern form a well-defined structure (-helix) indicating that a specific surface can stabilize the structure of an IDP peptide. The effect of a compleme
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Ns [102, 106]. In contrast, IDPs are charged proteins, thus they can control their interfacial absorption onto solid surfaces [106]. Experiments, in silico, suggest that intrinsically disordered peptides absorbed to a surface with a complementary pattern form a well-defined structure (-helix) indicating that a specific surface can stabilize the structure of an IDP peptide. The effect of a compleme
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Neutralization. However, in heterotypic dengue virus infections the antibodies are non-neutralizing and lead to enhancement. Two cell lines expressing either FcRIA or FcRIIA have been used to demonstrate that immune complexes can enhance virus infectivity in an FcR mediated fashion. FcRIA is found exclusively on macrophages and dendritic cells and preferentially binds monomeric IgG, while FcRIIA i
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Ne groups. On the other hand, no statistical difference was found between the control and the leaded groups. Serotonin content was not affected in all the three experimental groups when comparison was made between each other. In the hypothalamus, data in table 2 reveal that the norepinephrine, dopamine and serotonin in the group exposed to the unleaded gasoline were lower than those of the control
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Ells can increase viral RNA production by over 100-fold making dendritic cells potent components in dengue pathogenesis[20]. Infected dendritic cells also contribute to vascular leak through the production of matrix metalloproteinases (MMPs). MMP-2, MMP-13, and MMP-9 were all dramatically increased in immature dendritic cells infected with DENV2. As a result cell-cell adhesion in cells co-cultured
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Ne groups. On the other hand, no statistical difference was found between the control and the leaded groups. Serotonin content was not affected in all the three experimental groups when comparison was made between each other. In the hypothalamus, data in table 2 reveal that the norepinephrine, dopamine and serotonin in the group exposed to the unleaded gasoline were lower than those of the control
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Ce score B Age Gender Ethnicity Marital status Occupation Presence of chronic medical illness Perceived dangerous PSI value The actual PSI value at the time of survey Personal possession of N-95 mask Perceived usefulness of N-95 mask Total number of physical symptomsIES-R = Impact of Event Scale - Revised.Mean intrusion score SE RMean hyper-arousal score SE RTotal mean IES-R score SE RTotal IES-R
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