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Ased on NETPHOS software. We also includeAuthor Manuscript Author Manuscript Author Manuscript Author ManuscriptMatrix Biol. Author manuscript; available in PMC 2017 May 01.Boskey and Villarreal-RamirezPageSPARC (osteonectin), a protein involved with mineralization (linked in some ways to osteoporosis) that has some IDP regions. The SIBLINGs all bind to HA, however characterizing adsorption of pro
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Defect model in rabbits. The major merit of this study was that, this implant has been tested in vivo so that with a welldesigned pilot and experimental study we were able to explain the mechanism of action of this implant on tendon healing. In addition, we followed the immune activity of the body in response to the implanted collagen prosthesis from the early stages to four months after injury by
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Line resulted in decreased EGR2 expression (26). Chandra et al. demonstrate that the MAPK/ERK pathway is a major downstream signaling pathway mediating the stimulatory effects of EGF on EGR2 expression and osteoprogenitor survival [28]. Finally, To et al. report that the same MEK inhibitor utilized in our experiments, U0126, was the elicited the most potent inhibition of EGR2 transcription in brea
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, I54A 32, a very stable mutant, is more susceptible to ClpYQ and FtsH proteases than wild-type 32, indicating that the stability of 32 does not always reflect its susceptibility to proteases. Co-precipitation and gel filtration analyses show that purified 32 mutants exhibit a reduced affinity for DnaJ, leading to a marked decrease in forming a complex with DnaK in the presence of DnaJ and ATP. Ot
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