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Cist attitudes toward minorities--could not be confirmed as driving elements. What, then, could possibly be motifs to construct conspiracy theories Inside the following sections we present a theoretical framework which accounts for the subtle "shades of truth" revealed by narrative construction, as well as the co.Cist attitudes toward minorities--could not be confirmed as driving components. What,
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Ns [102, 106]. In contrast, IDPs are charged proteins, thus they can control their interfacial absorption onto solid surfaces [106]. Experiments, in silico, suggest that intrinsically disordered peptides absorbed to a surface with a complementary pattern form a well-defined structure (-helix) indicating that a specific surface can stabilize the structure of an IDP peptide. The effect of a compleme
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Noted in atypical breast lesions [49, 50]. Our studies suggest that loss of SFRP1 in epithelial cells can enhance TGF- mediated EGR2 expression and affect TGF- induced M2 polarization of macrophages. As M2 macrophages secrete growth factors, such as Wnt ligands and EGF, this could contribute to tumor progression through a feed forward cross talk between the epithelium and the immune system. Additi
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, I54A 32, a very stable mutant, is more susceptible to ClpYQ and FtsH proteases than wild-type 32, indicating that the stability of 32 does not always reflect its susceptibility to proteases. Co-precipitation and gel filtration analyses show that purified 32 mutants exhibit a reduced affinity for DnaJ, leading to a marked decrease in forming a complex with DnaK in the presence of DnaJ and ATP. Ot
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Mass consists of tumor-associated macrophages (TAMs) and poor prognosis is associated with elevated levels of TAMs [44]. Stimuli in the tumor environment polarize TAMs towards a protumor M2 rather than an anti-tumor M1 phenotype [45]. TGF- promotes tumor progression by recruiting TAMs to compete with dendritic cells by suppressing their antigen-presentation [34]. Zhang et al. provide evidence that