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Ed vaccines) or viruses (inactivated vaccines) inactivated by chemical or physicalEd vaccines) or viruses (inactivated vaccines) inactivated by chemical or physical treatmentsToxoids vaccinesPurified exotoxins chemically inactivated into toxoids that retain the ability to induce toxin-neutralizing antibodiesSubunit/ polysaccharide vaccinesAntigenic components of pathogens: partly or fully pu
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Veloping these vaccines. Live attenuated vaccine can eventually mutate into aVeloping these vaccines. Live attenuated vaccine can eventually mutate into a more virulent form capable of [5] causing diseases , whereas inactivated or killed vaccines and protein subunit vaccines generally generate weak [6] immune responses often requiring the use of adjuvants . Many live attenuated vaccines are
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An N-terminus with small acidic motif (DSpSpEE) that is also found in SIBLING proteins [65]. When solubilized, statherin has a random coil conformation. When bound to HA, it takes on a more alpha-helical structure exposing a bacterial binding site [63], leading to bacterial entrapment. Another example is the role of the IDP, DMP1, in preventing kidney and cardiovascular calcification. The double k
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Ving pathogens , these types of vaccines are usually safe compared toVing pathogens , these types of vaccines are usually safe compared to live attenuated vaccines. Overall, these technologies have allowed to achieve the successes of vaccinology in the last century and to produce the vaccine formulations available on the market. However many new vaccines are needed and for them , [8] new str
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Unteers' lung found significant decreases in levels of SP-A [28]. Unfortunately, there was little overlap in the sets of identified proteins between our studies and therefore little basis for comparison. When the DEF and RED proteins are individually examined as subgroups of the identified proteins, the changes are similar to those noted for all proteins. In both of these groups of proteins, more
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