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Gue that the stable and effective interaction of heat shock protein 70 (Hsp70) with a substrate polypeptide may generally require the simultaneous binding of heat shock protein 40 (Hsp40) to distinct sites on the substrate.Various cellular processes are controlled by the regulated degradation of key protein factors. Escherichia coli heat shock transcription factor 32 (encoded by the rpoH gene), wh
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