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Lore the effects of antibody upon exocytosis in vivo. Severe combined immunodeficient (SCID)/ beige mice received two human skin grafts that retain superficial dermal human microvessels. Five weeks after transplantation, we injected mice with the F(ab )2 portion of the antibody to HLA class I, or a control F(ab )2 antibody. After 1 or 6 h, the mice were killed, and the skin graft was harvested, em
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