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Riggering exocytosis, directly killing cells, or indirectly damaging Weibel alade bodies. Our cytotoxicity data above suggest that antibody to HLA class I does not kill endothelial cells directly (Figs. 1 D and E). To further show that antibody triggers regulated secretion of VWF from endothelialYamakuchi et al.Fig. 3. Effects of both C5a and antibody to HLA upon exocytosis. (A) C5a added to anti-

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